Their Premier League amusement at Stamford Bridge commences at 12:45 BST.
The Gunners were beaten in Croatia by Dinamo Zagreb in the Champions League on Wednesday, that day the Blues beat Maccabi Tel Aviv at home.
"I don't utilize that as a reason," said Wenger. "I trust we are in a position where we can perform."
Wenger goes for 'full power'
Wenger rolled out six improvements in Zagreb as he dropped manager Petr Cech, left-back Nacho Monreal, midfielder Francis Coquelin and forward Theo Walcott to the seat, while midfielder Aaron Ramsey and right-back Hector Bellerin were not in the squad.
Ramsey and Bellerin are back in conflict to play Chelsea, while Wenger says he has yet to choose whether Olivier Giroud, who was sent off in Croatia, or Walcott will begin.
"I defend my determination and assume liability for it," included the Frenchman. "I trust we can repair what happened.
"We are on a decent keep running in the Premier League and it is vital now to take a gander at that.
"Each annihilation harms however every thrashing is likewise a chance to react in an exceptionally solid manner."
Wenger declined to go into his bad tempered association with Chelsea partner Jose Mourinho or the battling begin his seventeenth put adversaries have had.
"I don't consider a lot of where Chelsea remains right now and I'm engaged more on us performing admirably with full power," he said.
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