Andy Murray beaten by Kevin Anderson in US Open fourth round

Andy Murray endured his most punctual Grand Slam exit for a long time as he lost a difficult fourth-round challenge against fifteenth seed Kevin Anderson.

The South African won 7-6 (7-5) 6-3 6-7 (2-7) 7-6 (7-0) in four hours and 18 minutes to achieve a first real quarter-last, where he confronts Stan Wawrinka.

It is the first run through since the 2010 US Open that Murray has lost before the quarter-finals of a Grand Slam.

Briton Jo Konta lost 7-5 6-3 to Petra Kvitova in the ladies' singles.