Triumph for Mrs Clinton was generally expected however it gives her force in front of the "Super Tuesday" primaries in 11 states one week from now.
"Tomorrow this crusade goes national," she told cheering supporters.
Mr Sanders has saluted her however said the battle was simply starting.
With every one of the votes tallied Mrs Clinton drives Mr Sanders by a just about 50-point edge.
CANDIDATE PERCENT VOTES
Hillary Clinton 73.48% 271,514
Bernie Sanders 25.97% 95,977
Willie Wilson 0.36% 1,321
Martin O'Malley 0.19% 714
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